Advanced Instrumentation Research Facility
1. Research Facilities
The School has “state-of-the-art” instrumentation facilities which are excellent for training in the modern areas of biological sciences. These include:
- Central Instrumentation Facility
- Recombinant Product Development Facility of GLP standard
- Spectroscopic Facility
- Microcalorimetric Facility
- Microscopic Facility
- Protein production and purification Facility
- Biosafety Level 3 Facility
Central Instruments Facility
The School has a Central Instruments Facility (CIF), equipped with all the basic and advanced equipments/instruments required for modern day research in biotechnology. The facility is open 24x7 for both the M.Sc. as well as the Ph.D. students.
Recombinant Product Development Facility of GLP standards (RPDF-GLP)
Under the FIST support from the Department of Science and Technology (DST), the School has created a Recombinant Product Development Facility of GLP standard, established in the newly constructed extension wing of the School of Biotechnology. The facility includes all necessary up stream and downstream equipments, and quality control and testing equipments required for the recombinant product development.
The facility created in the SBT at JNU is special, as it has the flexibility to be used for the production of both recombinant products as well as the purification and characterization of non-recombinant products. In a University set up, this flexibility allows one to take up new research projects without compromising the stringent requirements of a facility of GLP standard. The RPDF-GLP will help in enhancing Industry-academia interaction, and thus facilitating transfer of technologies by the scientists from academic institutes to the industry.
Spectroscopic facility:
The spectroscopic facility includes a number of highly sensitive UV-Visible spectrophotometers, Fluorescence spectrometers, Circular Dichroism spectrometer, FT-IR spectrometer.
Microcalorimetric facility:
This facility includes differential scanning calorimetric and isothermal titration calorimetric set up for studying bimolecular stability, folding and interactions.
Microscopic facility:
This includes Simple microscopes, Fluorescent microscopes, Laser Scanning Confocal microscope, Phase contrast microscopes.
Protein Production and Purification Facility
This facility includes refrigerated incubator shakers, Bacterial and Mammalian cell bioreactors with online FTIR analysis, AKTA-Prime, AKTA-Explorer FPLC protein purification systems, Shimadzu HPLC protein purification system.
Other equipments:
Other specialized analytical facilities that are available in various labs and the Central facility include Real Time PCR, ELISA readers, Elispot Reader and Fluorescence Activated Cell Sorter etc.
DBT- supported Biosafety Level 3 Laboratory (BSL3) :
The Biosafety Level 3 laboratory has been running since 2010 thanks to the financial support provided by the Department of Biotechnology, Ministry of Science of Technology, New Delhi. The facility will strengthen our infrastructure for research and development in the areas of infectious diseases. It is also used for research involving manipulation of biological infectious agents, both indigenous or exotic, which may cause serious or potentially lethal disease as a result of exposure by the inhalation route, with special reference to Bacillus anthracis. Working with pathogens in their virulent form is helping us understand the mechanisms by which these agents cause disease and thereby open up avenues that can be used for intervention during the setting or progression of the diseases. This is helping in developing new vaccines and therapeutics.
2. School’s Library and Computer Lab:
The School library is mainly supported by the funds from the Department of Biotechnology. It has over 700 books in different areas of teaching and research in Biotechnology. The library also subscribes to a number of scientific journals.
The Computer lab houses a number of computers which are available to the students of the School for carrying out their assignments in different courses such as bioinformatics and computational biology, besides helping in online database searches and literature search.