Krishnamurthy Natarajan
              Professor
           Laboratory of Eukaryotic Gene Regulation
           314/325, School of Life Sciences
           Jawaharlal Nehru University
           New Delhi 110067, India.
           Phone: (011)26704512 (Lab/Office)
           E-mail: nat0200@mail.jnu.ac.in

         

 
 JNU  Research  Publication  Data  Course  People

 
 

Publications (Selected peer-reviewed):

  • Srivastav, M.K., Agarwal, N., and Natarajan, K. (2018). Multiple Evolutionarily Conserved Domains of Cap2 Are Required for Promoter Recruitment and Iron Homeostasis Gene Regulation. mSphere 3, e00370-00318.

  • Dahiya, R., and Natarajan, K. (2018). Mutational Analysis of TAF6 Revealed the Essential Requirement of the Histone-fold Domain and the HEAT Repeat Domain for Transcriptional Activation. The FEBS Journal 285, 1491–1510.

  • Singh, A., Gotherwal, V., Junni, P., Vijayan, V., Tiwari, M., Ganju, P., Kumar, A., Sharma, P., Fatima, T., Gupta, A., Holla, A., Kar, H. K., Khanna, S., Thukral, L., Malik, G., Natarajan, K., Gadgil, C.J., Lahesmaa, R., Natarajan, V.T., Rani, R., Gokhale, R.S. (2017). Mapping architectural and transcriptional alterations in non-lesional and lesional epidermis in vitiligo. Scientific Reports 7, 9860.

  • Srivastav, M.K., Nair, R., and Natarajan, K. (2017). Iron Acquisition in the Pathobiology of Candida albicans. In Candida albicans: Cellular and Molecular Biology, R. Prasad, ed. (Cham: Springer International Publishing), pp. 347-378.

  • Sinha I, Poonia P, Sawhney S, Natarajan K. (2017) Functional Specialization of Two Paralogous TAF12 Variants by Their Selective Association with SAGA and TFIID Transcriptional Regulatory Complexes. Journal of Biological Chemistry 292: 6047–6055.

  • Priyadarshini, Y. and Natarajan K. (2016). Reconfiguration of Transcriptional Control of Lysine Biosynthesis in Candida albicans Involves a Central Role for the Gcn4 Transcriptional Activator. mSphere (ASM Press) 1: e00016-00015.

  • Saint, M*, Sawhney, S*, Sinha, I, Singh R.P., Thakur, A., Siddharthan, R. and Natarajan K. (2014). TAF9 C-terminal conserved region domain is required for SAGA and TFIID promoter occupancy to promote transcriptional activation. Molecular and Cellular Biology 34(9): 1547-63. *equal contribution.

  • Natarajan, V.T., Ganju, P., Singh, A., Vijayan, V., Kirty, K., Yadav, S., Puntambekar, S., Bajaj, S., Dani, P., Kar, H.K., Gadgil, C.J., Natarajan, K., Rani, R. and Gokhale, R.S. (2014). IFN-? signaling maintains skin pigmentation homeostasis through regulation of melanosome Maturation. Proc. Natl. Acad. Sci. (USA) 111:2301-2306.

  • Singh, R.P., Prasad, H.K., Sinha, I., Agarwal, N. and Natarajan, K. (2011) Cap2-HAP Complex Is a Critical Transcriptional Regulator That Has Dual but Contrasting Roles in Regulation of Iron Homeostasis in Candida albicans. Journal of Biological Chemistry, 286, 25154-25170.

  • Natarajan, K*., Marton, M.J. and Hinnebusch, A.G. (2007). Principles and Practice of DNA Microarray Technology. In Methods in General and Molecular Microbiology, ASM Press, USA. 978-994. (*Invited chapter and Corresponding Author)

  • Qiu, H., Hu, C., Yoon, S., Natarajan, K., Swanson, M.J. and Hinnebusch AG. (2004). An array of coactivators is required for optimal recruitment of TATA binding protein and RNA polymerase II by promoter-bound Gcn4p. Molecular and Cellular Biology 24, 4104-4117.

  • Swanson, M.J., Qiu, H., Sumibcay, L., Krueger, A., Kim, S., Natarajan, K., Yoon, S., and Hinnebusch AG. (2003). A multiplicity of coactivators is required by Gcn4p at individual promoters in vivo. Molecular and Cellular Biology 23, 2800-2820.     

  • Hinnebusch, A.G. and Natarajan, K. (2002). Gcn4p, a master regulator of gene expression, is controlled at multiple levels by diverse signals of starvation and stress. Eukaryotic Cell 1:22-32.

  • Natarajan, K., Meyer, M.R., Jackson, B.M., Slade, D., Hinnebusch, A.G. and Marton, M.J. (2001). Transcriptional Profiling Shows that Gcn4p is a Master Regulator of Gene Expression During Amino Acid Starvation in Yeast. Molecular and Cellular Biology 21, 4347-4368. 

  • Natarajan, K., Jackson, B.M., Zhou, H., Winston, F. and Hinnebusch, A.G. (1999). Transcriptional Activation by Gcn4p Involves Independent Interactions with SWI/SNF Complex and SRB/Mediator Molecular Cell 4, 657-664.

  • Natarajan, K., Jackson, B.M., Rhee, E., and Hinnebusch, A.G. (1998). yTAFII61 Has a General Role in RNA Polymerase II Transcription and is Required By Gcn4p to Recruit the SAGA Coactivator Complex. Molecular Cell 2, 683-692.

  • Jackson, B.M., Drysdale, C.M., Natarajan, K. and Hinnebusch, A.G. (1996). Identification of Seven Hydrophobic Clusters in GCN4 Making Redundant Contributions to Transcriptional Activation. Molecular and Cellular Biology 16, 5557-5571.

  • Kumar MJ, Jamaluddin MS, Natarajan K, Kaur D. and Datta, A. (2000). The inducible N-acetylglucosamine catabolic pathway gene cluster in Candida albicans: Discrete N-acetylglucosamine-inducible factors interact at the promoter of NAG1. Proc. Natl. Acad. Sci. (USA). 97,14218-14223.

  • Natarajan, K. and Datta, A. (1993). Molecular Cloning and Analysis of the NAG1 cDNA Coding for Glucosamine 6-Phosphate Deaminase from Candida albicans. Journal of Biological Chemistry 268, 9206-9214.