Research Area
We are currently investigating the role of sleep in memory consolidation and its underlying cellular and molecular mechanisms.
The key questions that we are currently addressing in the lab are
· Does sleep play an instructive or a permissive role in memory consolidation?
· Does sleep facilitate memory consolidation by directly activating the cellular and molecular signaling pathways in the brain?
· Does sleep enhance memory by activating neurogenesis in the hippocampus?
· Does REM sleep function to maintain bodily normocapnia to avoid frequent arousals from sleep?
Learning induced changes in protein kinase and CREB levels in the brain
|
Adult Neurogenesis and learning and memory |
|||||
|
|
Research Grants:
§ The induction of compensatory neural circuitries and the role of NMDA receptor and sleep in the consolidation of Conxt-FC memory in the absence of the dorsal hippocampus in the rat.
Funded by DBT, 2017-2021.
§ The Brainstem Chemosensory machinery: A novel target for sleep regulation and cognitive functions.
Funded by DST, 2017-2021.
§ Synthesis of core-shell magnetic nanoparticles, their possible use in brain tumor detection, treatment and recovery in cognitive functions.
Funded by UPOE-II, 2014-2019.
§ The role of amygdalar neurons and glia in sleep depended consolidation of cued fear-conditioned memory in the rat. Funded by DST, 2011-2016.
§ The role of sleep in the consolidation of fear-conditioned memory in the rat. Funded by CSIR, 2008-2012.
§ Role of sleep in consolidation of conditioned-reward memory in the rat. Funded by DBT, 2008-2012.