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Ajay Kumar Saxena

Ajay Kumar Saxena

Ajay Kumar Saxena
Ajay Kumar Saxena
Professor
Centre/School/Special Centre
School of Life Sciences
Room No
403
Off. Phone
011-26704155
Email
ajaysaxena@mail.jnu.ac.in
Personal Webpage
https://jnu.ac.in/Faculty/asaxena/cv.pdf
Qualifications

Ph.D. in Protein Crystallography 

Areas of Interest/Specialization

Structural Biology on Disease related proteins, Structure guided Drug/Vaccine development 

Experience
03/2011- Present Professor, Structural Biology Section, Jawaharlal Nehru University, India.
2005-2011 Associate Professor, Structural Biology Section, Jawaharlal Nehru University, India.
1998-2005 Research Fellow, Structural Biology Section, NIAID, National Institutes of Health, USA.
1996-1998 Postdoctoral Fellow, Institute of Biophysics & X-ray Structure Research, Austrian Academy of Sciences, Austria, Europe  
Awards & Honours
  1. NPG group, Bill & Melinda gates foundation travel award to attend GRC
  2. John E. Fogatry International Fellowship, NIH, USA
  3. Austrian Academy of Science Fellowship, OAW, Austria, Europe
  4. Senior Research Fellowship, DBT, India 
International Collaboration/Consultancy
  1. Dr. Shiv Srivastava, Scientific Director, CPDR, USUHS, USA
  2. Dr. David N. Garboczi, NIAID, NIH, USA 
Best Peer Reviewed Publications
  1. Arkita Bandhopadhyay and Ajay K. Saxena# (2021). Structural and ATPase activity analysis of nucleotide binding domain of Rv3870 enzyme of M. tuberculosis ESX-1 system.
    Int. J. Biol. Macromol 189: 879–889.
  2. Sumita Karan, Ankita Behl, Amin Sagar, Arkita Bandhopadhyay and Ajay K. Saxena# (2021). Structural studies on Mycobacterium tuberculosis HddA enzyme using small angle X-ray scattering and dynamics simulation techniques,
    Int. J. Biol. Macromol.171:28-36.
  3. S. Karan, B. Pratap, Shiv P. Yadav, FNU. Ashish & Ajay K. Saxena# (2020). Structural and functional characterization of M. tuberculosis sedoheptulose‑7‑phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway.
    Nature Sci. Rep. 10(1):20813.
  4. Manford, T. Xia, A. K. Saxena, C. Stefan, F. Hu, S. D. Emr and Y. Mao (2010). Crystal structure of the yeast Sac1: implications for its phosphoinositide phosphatase function (PDB-3LWT).
    EMBO J. 29(9), 1489-1498.
  5. Saxena, A. K.#, Singh, K., Su, H.P., Klein, M. M., Stower, A. W., Saul, A. J., Long, C. and Garboczi, D. N. (2006). Plasmodium P25 and P28, essential proteins for survival of the malaria parasite in the mosquito is tile-like triangular prism (PDB-1Z27, 1Z1Y, 1Z3G).
    Nature (Struc. & Mol. Biol.) 13(1), 90-91.
Recent Peer Reviewed Journals/Books
  1. Yeshveer Singh, Ruby Sharma, Manasi Mishra, Praveen Kumar Verma# and Ajay K. Saxena# (2021). Crystal structure of ArOYE6 reveals a novel C-terminal fold and mechanistic insights into the distinct class III OYEs from pathogenic fungi.
    The FEBS Journal. 2022 Mar 21
  2. Arkita Bandhopadhyay and Ajay K. Saxena# (2021). Structural and ATPase activity analysis of nucleotide binding domain of Rv3870 enzyme of M. tuberculosis ESX-1 system.
    Int. J. Biol. Macromol 189: 879–889.
  3. Sumita Karan, Ankita Behl, Amin Sagar, Arkita Bandhopadhyay and Ajay K. Saxena# (2021). Structural studies on Mycobacterium tuberculosis HddA enzyme using small angle X-ray scattering and dynamics simulation techniques.
    Int. J. Biol. Macromol.171:28-36.
  4. S. Karan, B. Pratap, Shiv P. Yadav, FNU. Ashish & Ajay K. Saxena# (2020). Structural and functional characterization of M. tuberculosis sedoheptulose‑ 7‑phosphate isomerase, a critical enzyme involved in lipopolysaccharide biosynthetic pathway.
    Nature Sci. Rep. 10(1):20813.
  5. Sumita Karan, Bhanu pratap, Ashish and Ajay K. Saxena# (2019). Low-resolution SAXS and structural dynamics analysis on M. tuberculosis GmhB enzyme involved in GDP- heptose biosynthetic pathway.
    Int. J. Biol. Macromol. 136: 676–685.

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.