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Manoj Munde

Manoj Munde

Manoj Munde
Manoj Munde
Assistant Professor
Centre/School/Special Centre
School of Physical Sciences
Off. Phone
011-26738933
Residence
09910052147
Email
mmunde@mail.jnu.ac.in , mundemanoj@gmail.com
Personal Webpage
http://biophysicalchemistrylabsps.in
Qualifications

Ph.D. (2006, IIT Bombay)

Areas of Interest/Specialization

Biophysical Chemistry, Thermodynamics and kinetics, Biomolecular complexes of proteins, DNAs and Drugs

Experience

Aug 2014-Present Assistant Professor, School of Physical Sciences, Jawaharlal Nehru University, New Delhi
Sept 2013-Aug 2014 Assistant Professor, Central University of Rajasthan, Bandarsindri, Ajmer, Rajasthan
Oct 2010-Aug 2013 Research Associate, Georgia State University, Atlanta, USA
Jan 2006-Sept 2010 Postdoctoral Associate, Georgia State University, Atlanta, USA 

Awards & Honours

Selected as UGC Assistant Professor under UGC Faculty Recharge Program (2013)
Awarded NIH postdoctoral fellowship (2006) 
Awarded Teaching Assistantship at IIT Bombay (2001) 

Best Peer Reviewed Publications

* An Unusual Monomer Recognition of Guanine Containing Mixed Sequence DNA by a Dithiophene Heterocyclic Diamidine. Munde M, Kumar A, Peixoto P, Depauw S, Ismail MA, Farahat AA, Paul A, Say MV, David-Cordonnier MH, Boykin DW, Wilson WD. Biochemistry (2014) 53, 1218-27
* Structure-dependent inhibition of the ETS-family transcription factor PU.1 by novel heterocyclic diamidines. Munde M, Wang S, Kumar A, Stephens CE, Abdelbasset A. Farahat, Boykin DW, Wilson WD, Poon GM. Nucleic Acid Research (2014) 42, 1379-90
* DNA minor groove induced dimerization of heterocyclic cations: compound structure, binding affinity, and specificity for a TTAA site. Munde, M., Kumar, A., Nhili, R., Depauw, S., David-Cordonnier, M. H., Ismail, M. A., Stephens, C. E., Farahat, A. A., Batista-Parra, A., Boykin, D. W., and Wilson, W. D., J Mol Biol (2010) 402, 847-864.
* Induced fit conformational changes of a reversed amidine heterocycle:optimized interactions in a DNA minor groove complex. Munde, M., Lee, M., Neidle, S., Arafa, R., Boykin, D. W., Liu, Y., Bailly, C., and Wilson, W. D., J Am Chem Soc (2007) 129, 5688-5698.
* Design of DNA minor groove binding diamidines that recognize GC base pair sequences: a dimeric-hinge interaction motif. Munde, M., Ismail, M. A., Arafa, R., Peixoto, P., Collar, C. J., Liu, Y., Hu, L., David-Cordonnier, M. H., Lansiaux, A., Bailly, C., Boykin, D. W., and Wilson, W. D., J Am Chem Soc (2007) 129, 13732-13743. 

Recent Peer Reviewed Journals/Books

* Mechanistic Heterogeneity in Site Recognition by the Structurally Homologous DNA-Binding Domains of the ETS-Family Transcription Factors Ets-1 and PU.1Sang S, Linde MH, Carvalho V, Munde M, Wilson WD, Poon G, Journal of Biological Chemistry (2014) 289, 21605-16.
* Probing the electrostatics and pharmacologic modulation of sequence-specific binding by the DNA-binding domain of the ETS-family transcription factor PU.1: a binding affinity and kinetics investigation. Munde M, Poon GM, Wilson WD., J Mol Biol. (2013) 425, 1455-59.

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.