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K. Natarajan

K. Natarajan

K. Natarajan
K. Natarajan
Professor
Centre/School/Special Centre
School of Life Sciences
Room No
325
Off. Phone
011-26704512
Email
nat0200@mail.jnu.ac.in
Personal Webpage
https://www.jnu.ac.in/Faculty/natarajan
Qualifications

Ph.D.

Areas of Interest/Specialization

Broad area of research- Cell and Molecular biology/Molecular genetics: Transcription, chromatin and gene regulation

Specific areas-

(1) TAF complexes and Mechanism of Transcription in Saccharomyces cerevisiae and Candida albicans;

(2) Gene regulation during Iron Homeostasis in Candida albicans

(3) Transcriptional Regulatory Network controlling Melanogenesis and pigment disorders using Mouse Melanoma cell lines 

Experience

Teaching: 2001 - present; Research: 1994 - present
Mentor/Supervisor:
Ph.D. - 04 (current); 10 (awarded)
M.Sc. - 24 (awarded)  

Awards & Honours

Elected Fellow, National Academy of Sciences, Allahabad, India
DBT-CREST Award, Department of Biotechnology, Ministry of Science and Technology, Govt. of India.
Full Member- American Society for Biochemistry and Molecular Biology
Member- American Society for Microbiology
EMBL Travel Award, 9th Transcription and Chromatin Conference held at EMBL, Heidelberg, Germany
Fellows Award for Research Excellence, NIH, Bethesda, MD. (1998)
National Research Fellowship (NET-JRF), University Grants Commission/Council of Scientific and Industrial Research, New Delhi, India.
Adhoc Reviewer:
Journals: PLOS One, Molecular Microbiology, Molecular and Cellular Biology, Microbiology, Applied and Environmental Microbiology; and various Indian Journals.
Grants: DBT, DST, CSIR 

International Collaboration/Consultancy

Dr. Rajesh Gokhale, CSIR-Institute for Genomics and Integrative Biology, Delhi
Dr. Jerry Workman, Stowers Institute for Medical Research, Kansas City, MO, USA. 

Best Peer Reviewed Publications
  • Sinha I, Poonia P, Sawhney S, Natarajan K. (2017) Functional Specialization of Two Paralogous TAF12 Variants by Their Selective Association with SAGA and TFIID Transcriptional Regulatory Complexes. Journal of Biological Chemistry 292: 6047–6055.
  • Saint, M*, Sawhney, S*, Sinha, I, Singh R.P., Thakur, A., Siddharthan, R. and Natarajan K. (2014). TAF9 C-terminal conserved region domain is required for SAGA and TFIID promoter occupancy to promote transcriptional activation. Molecular and cellular Biology 34(9): 1547-63. *equal contribution
  • Natarajan, V.T., Ganju, P., Singh, A., Vijayan, V., Kirty, K., Yadav, S., Puntambekar, S., Bajaj, S., Dani, P., Kar, H.K., Gadgil, C.J., Natarajan, K., Rani, R. and Gokhale, R.S. (2014). IFN-g signaling maintains skin pigmentation homeostasis through regulation of melanosome Maturation. Proc. Natl. Acad. Sci. (USA) 111:2301-2306.
  • Singh, R.P., Prasad, H.K., Sinha, I., Agarwal, N. and Natarajan, K. (2011) Cap2-HAP Complex Is a Critical Transcriptional Regulator That Has Dual but Contrasting Roles in Regulation of Iron Homeostasis in Candida albicans. Journal of Biological Chemistry, 286, 25154-25170.
  • Natarajan, K., Meyer, M.R., Jackson, B.M., Slade, D., Hinnebusch, A.G. and Marton, M.J. (2001). Transcriptional Profiling Shows that Gcn4p is a Master Regulator of Gene Expression During Amino Acid Starvation in Yeast. Molecular and Cellular Biology 21, 4347-4368.  
Recent Peer Reviewed Journals/Books
  • Sinha I, Poonia P, Sawhney S, Natarajan K. (2017) Functional Specialization of Two Paralogous TAF12 Variants by Their Selective Association with SAGA and TFIID Transcriptional Regulatory Complexes. Journal of Biological Chemistry 292: 6047–6055.
  • Srivastav MK, Nair R, Natarajan K (2017) Iron Acquisition in the Pathobiology of Candida albicans. In: Prasad R, editor. Candida albicans: Cellular and Molecular Biology. Cham: Springer International Publishing. pp. 347-378.
  • Priyadarshini Y., Natarajan, K. (2016) Reconfiguration of transcriptional control of lysine biosynthesis in Candida albicans involves a central role for the Gcn4 transcriptional activator. mSphere (ASM Press) 1: e00016-00015. 
Patents (if any)

United States Patent# 5547870 entitled "Oxalate Decarboxylase" by Datta, A., Mehta, A. and Natarajan, K. 

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.