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Rajiv Bhat

Rajiv Bhat

Rajiv Bhat
Rajiv Bhat
Professor
Centre/School/Special Centre
School of Biotechnology
Room No
104
Off. Phone
011-26704086
Residence
011-26738747
Email
rajivbhat@mail.jnu.ac.in, rajivbhat@hotmail.com
Personal Webpage
https://jnu.ac.in/Faculty/rajivbhat
Qualifications

Ph.D. (Biophysical Chemistry), IIT, Delhi (1986)
M.Sc. (Physical Chemistry), University of Jammu (1980)
B.Sc. (Biology and Chemistry), University of Jammu (1978)

Areas of Interest/Specialization
  • Aggregation and Amyloid formation in neurodegenerative and other diseases. Discovery of natural products as potential inhibitors and modulators of aggregation-related diseases. Intrinsically disordered proteins and protein homeostasis
  • Bimolecular Structure and Interactions: Role of water and weak interactions
  • Use of Chemical Chaperones in controlling protein misfolding and amyloid formation
  • Structural and functional stabilization of proteins and enzymes by stress-osmolytes and technology development for stabilizing therapeutic proteins      
Experience

2004-    : Professor, School of Biotechnology, JNU, New Delhi.
1998-2004: Associate Professor, Special Centre for Biotechnology, JNU, New Delhi.
2000-2001: Visiting Scientist, Department of Chemistry and Chemical Biology, Cornell
University, Ithaca, NY, USA.
1990-1998: Assistant Professor, Special Centre for Biotechnology, JNU, New Delhi.
1989-1990: Lecturer, Department of Biochemistry, University of Delhi, New Delhi.
1986-1989: Postdoctoral Associate, Graduate Department of Biochemistry, Brandeis University, Waltham, Massachusetts, USA.
1985-1986: Lecturer in Chemistry, Thapar Institute of Engineering and Technology, Patiala.

Dean, School of Biotechnology, Jawaharlal Nehru University, New Delhi (2009-2011)
Director of Admissions, Jawaharlal Nehru University, New Delhi (2011-2013)
Programme Coordinator, Inter-School project in the area of “Chemical and Synthetic Biology” (DBT-BUILDER) involving five Science Schools of JNU (2012-17)
Secretary, Indian Biophysical Society (2011-2015)

Awards & Honours
  • Merit Certificate for I rank in College/University in Pre-University Course,
  • Merit Certificate for I rank in College B.Sc.
  • Merit Certificate for I rank in M.Sc. Chemistry
  • National Merit Scholarship for postgraduate studies
  • Awarded Junior and Senior research fellowships of IIT, Delhi.
  • Postdoctoral Research Fellowship of National Institutes of Health (USA).
  • Young Investigator Travel Award of 'The Protein Society' to participate in their Second Symposium in San Diego, USA, 1988.
  • Biotechnology Overseas Associateship Award, Department of Biotechnology, Govt. of India, 2000-2001.
Best Peer Reviewed Publications
  1. Comparative analysis of the conformation, aggregation, interaction, and fibril morphologies of human α, β, and γ synuclein proteins, M. K. Jain, P. Singh, S. Roy, and R. Bhat, Biochemistry, 57(26), 3830–3848 (2018).
  2. Resveratrol interferes with an early step in the fibrillation pathway of human lysozyme and modulates it towards less-toxic, off-pathway aggregates, F. K. Zaidi and R. Bhat, ChemBiochem, 19, 159-170 (2018).    
  3. Modulation of human α-synuclein aggregation by a combined effect of calcium and dopamine, M. Jain and R. Bhat, Neurobiology of Disease, 63, 115-128 (2014).    
  4. Efficient refolding of aggregation prone citrate synthase by polyol osmolytes: How   well are folding and stability aspects coupled? R. Mishra, R. Seckler, and R. Bhat J. Biol. Chem., 280, 15553-15560 (2005).     
  5. Why is trehalose an exceptional protein stabilzer?: An analysis of the thermal stability of proteins in the presence of the compatible osmolytetrehalose, J. K. Kaushik and R. Bhat, J. Biol. Chem., 278, 26458-26475 (2003).   

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.