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Ranjana Arya

Ranjana Arya

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Ranjana Arya
Assistant Professor
Centre/School/Special Centre
School of Biotechnology
Off. Phone
011-26738754
Email
ranjanaa@mail.jnu.ac.in , arya.ranjana24@gmail.com
Personal Webpage
http://www.jnu.ac.in/Faculty/rarya
Qualifications

Ph.D 

Areas of Interest/Specialization

Cell Biology of Rare genetic disorders

Experience

2008-present Assistant Professor, School of Biotechnology, JNU, New Delhi
2004-2008 Senior Research Scientist, Ranbaxy Research Laboratories, Gurgaon
2002-2004 Post Doctoral Associate, Carolina Cardiovascular Center, University of North Carolina, Chapel Hill, USA
2001-2002 Post Doctoral Fellow, Division of Rheumatology, Immunology & Allergy, Brigham & Women’s Hospital, Harvard Medical School, Boston, USA 

Awards & Honours

GRANTS
• Arya R.: Functional analysis of UDP-N-acetylGlucosamine 2-epimerase/N-acetyl Mannosamine kinase (GNE) in cytoskeletal organization" SERB, DST, File No. EMR/2015/001798 dated: 27-4-2016.
• Arya,R.Structural and functional characterization of UDP N-acetylglucosamine 2-epimerase/N-acetyl mannosamine kinase (GNE). DST PURSE II, PAC-JNU-DST-PURSE-462 (Phase II)
• Arya, R. Effect of altering sialic acid metabolism on cell function. Project. UPOE II. ID: 16, dated:7th oct.2014-2019
• Arya, R. ‘Manipulation of sialic acid biosynthetic pathway using GNE and its effect on cytoskeletal organization’ CSIR, Extramural Research Division, 1-1-12 to 1-1-15. Sanction order No. 37(1512)/11/EMR-II
• Arya R. Possible role of key sialic acid biosynthetic enzyme (UDP-N-acetylglucosamine 2-epimerase/Mannosamine kinase) in apoptosis. ICMR. Sanction order No. 80/5/2010-BMS RFC No. BMS/adhoc/109/2011-12 dated 29-3-12
• Fast Track Scheme for Young Scientist from Department of Science and Technology for research project entitled’ Expression and characterization of bifunctional enzyme UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase in Dictyostelium discoideum. Sanction order No. SR/FT/LS-146/2008 dated Sept.22, 2009.

Oral Presentation
• Ranjana Arya, Vishram Kedar, Jae Roung Hwang, Holly McDonough, Hui-Hua Li, Joan Taylor and Cam Patterson. Muscle Ring Finger Protein, MURF1, Inhibits Cardiac Muscle Hypertrophy Through PKC Mediated Signaling Pathway. American Heart Association Scientific Sessions, 2004, New Orleans, USA (Oral Presentation). Source: CIRCULATION Volume: 110 Issue: 17 Pages: 160-160 Supplement: Suppl. S Meeting Abstract: 762 Published: OCT 26 2004

Award/Honour
• Young Scientist travel fellowship Award to attend 18th International Congress of Biochemistry and Molecular Biology held in Birmingham, England, 2000.
• Junior research fellowship award to pursue doctoral studies and Lecturership (1995) from Council of Scientific and Industrial Research, India.
• GATE qualified with a score of 97.34, India. (1996) 

Best Peer Reviewed Publications (upto 5)
  1. Singh, R. , Choudhary, P and Arya, R*.  IGF-1 rescues cell death of HEK 293 based model cells for GNE myopathy, 2018, Scientific Reports  doi. 10.1038/s41598-018-25510-9
  2. Chanana, P, Padhy, G, Bhargava, K and Arya, R*. Mutation in GNE downregulates Peroxiredoxin IV altering  ER redox homeostasis, Neuromolecular Medicine (2017) doi 10.1007/s12017-017-8467-5
  3. Singh, R and Arya, R*. GNE myopathy and cell apoptosis: a comparative mutation analysis. Mol. Neurobio., 2015, doi 10.1007/s12035-015-9191-5 PMID:25976366
  4. Grover S, Aslam S, Sharma V & Arya R* (2014) Expression and secretion of GNE and its mutants in Dictyostelium discoideum. CNS and neurological disorders-DT (2014), 13:7, 1263-1272 (I.F. 3.77)
  5. Grover, S and Arya R*. Role of UDP- N -Acetylglucosamine2-Epimerase/ N -Acetylmannosamine Kinase (GNE) in ß1-Integrin-Mediated Cell Adhesion. Molecular Neurobiology, 2014, 50(2); 257-273 (IF-5.47)
Recent Peer Reviewed Journals/Books (upto 3)

1. Grover, S and Arya R. Role of UDP- N -Acetylglucosamine2-Epimerase/ N -Acetylmannosamine Kinase (GNE) in ß1-Integrin-Mediated Cell Adhesion. Mol. Neurobiol. DOI: 10.1007/s12035-013-8604-6. (IF-5.7)

2. Tu, C, Ortega-Cava,C.F., Winograd, P., Stantona, M.J., Reddi, A.L., Dodge, I., Arya, R., Dimri, M., Clubba, R.J., Naramura, M., Wagnera, K., Band,V. ,and Band, H. Endosomal sorting complex required for transport (ESCRT) pathway-dependent late endosome/lysosome traffic regulates the localization of active Src at focal adhesions. Proc. Natl. Acad. Sci. USA, 2010, 107 (37), 16107-12 (I.F-9.68)

3. Singh, D, Rani, R., Rajendran, R., Kaur NJ., Pandey, A., Chopra, P., Jain, T., Jain, M., Grover, S., Arya, R. and Saini, KS. Human spleen tyrosine kinase, Syk, recombinant expression system for high throughput assays. Biotechnol. J., 2010, 5 (2), 201-212 (I.F.-3.44) 

Patents (if any)

Patent: Arya, R., Bhattacharya, A., Aslam, S., Bora, R.S., Gupta, S. and Saini, K.S.
Production of purified recombinant human phosphodiesterase in Dictyostelium discoideum
Arya R, Bhattacharya A, Aslam S, Bora RS, Gupta S, Saini KS
Ref. No: IN200701779-I1, Year: 08/2007

Patent: Malik, R., Bora, R.S., Arya, R., Gupta, D., Singh, V. and Saini, K.S.
A reporter gene assay for identifying a compound as selective inhibitor of PDE 4 subtype.
Malik R, Bora RS, Arya R, Gupta D, Singh V, Saini KS
Ref. No: IN200602547-I1, Year: 01/2006  

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.