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Samudrala Gourinath

Samudrala Gourinath

Samudrala Gourinath
Samudrala Gourinath
Professor
Centre/School/Special Centre
School of Life Sciences
Room No
430
Off. Phone
011-26704513
Email
sgourinath@mail.jnu.ac.in
Personal Webpage
http://jnu.ac.in/Faculty/gourinath/
Personal files
CV
Qualifications

1999 Ph.D. Biophysics, Crystallography, All India Institute of Medical Sciences, New Delhi, India
1995 M.Sc. BioTechnology University of Pune, Pune, India
1992 B.Sc. (Tech), Chemical Technology Loyola Academy, Osmania University, Hyderabad, India 

Areas of Interest/Specialization

Structural and Functional studies of crucial pathway enzymes / proteins from E. histolytica & H. pylori
i) Cysteine Biosynthetic pathway, sulfur metabolism in E. histolytica
ii) Crucial signaling and cytoskeletal proteins involved in Phagocytic cup formation in E. histolytica
iii) Replication initiation proteins from H. pylori. 

Experience


* July 2015 – present- professor, School of life Sciences, Jawaharlal Nehru University, New Delhi-110067, India. 
* 2016 – Guest faculty, Department of Biotechnology, South Asian University, New Delhi 
* 2012-July 2015. Associate professor, School of life Sciences, Jawaharlal Nehru University, New Delhi-110067, India.
* 2003- 2012. Assistant Professor, School of life Sciences, Jawaharlal Nehru University 

Awards & Honours

* Awarded National Bioscience Award for Career Development 2013 (announced in May 2014) by Department of Biotechnology, Government of India
* Indo-US science and Technology Forum fellowship for 2010, Visited Prof. Niko Gregorif, HHMI, Brandeis University
* Innovative Young Biotechnologist Award for 2006 (IYBA-2006) by Department of Biotechnology, Ministry of Science and Technology, Govt of India.
* Awarded DAAD (German academic exchange service) fellowship for short term, 1998.
* 1996. Qualified for the JRF/NET Fellowship awarded by the Council for Scientific and Industrial Research, Government of India.
* 1996. Qualified the Graduate Aptitude Test in Engineering (percentile score 95.43).
* 1993-1995. Department of Biotechnology, Ministry of Science & Technology, Government of India fellowship for MSc Biotechnology 1993-1995
* 1987-1989. Awarded the Telugu Vignana Parithoshikam (Andhra Pradesh state merit scholarship) by State Govt. Andhra Pradesh.
* 1987. Awarded the National merit scholarship by Govt. of India.  

 

Membership of Scientific Organizations

Elected Fellow of Indian National Science Academy - 2019

Elected to GRC-2016

Elected Fellow of Telengana Academy of Sciences - 2016
Elected Fellow of AP Academy of Sciences - 2016 

International Collaboration/Consultancy

Sponsoring Agency : Department of BioTechnology (Indo-German grant) 
Duration: 2010 - 2013 
Collaborator: Prof. Ch. Betzel
University of Hamburg Institute of Biochemistry and Molecular Biology 
Laboratory for Structural Biology of Infection and Inflammation c/o DESY, Build. 22a Notkestr. 85 22603 Hamburg Germany  

Best Peer Reviewed Publications
1. S Dharavath, I Raj, S Gourinath (2017) Structure-based mutational studies of O-Acetylserine Sulfhydrylase reveal the reason for the loss of cysteine synthase complex formation in Brucella abortus. Biochemical J. BCJ20161062

2. Preeti Pandeya,b, Khaza Faisal Tariquea, Mohit Mazumdera, Syed Arif Abdul Rehmana, Nilima kumarib and S. Gourinath. (2016) Structural insight into ß-Clamp binding site in DNA Ligase of Helicobacter pylori. Scientific Reports. 6:31181

3. Sanjeev Kumar, Saima Aslam, Mohit Mazumder, Pradeep Dahiya, Aruna Murmu, Babu A. Manjasetty, Rana Zaidi, Alok Bhattacharya and S. Gourinath (2014) Crystal Structure of Calcium Binding Protein-5 from Entamoeba histolytica and its involvement in initiation of phagocytosis of human erythrocytes. PLoS Pathogens. 10(12):e1004532.

4. Singh RK, Raj I, Pujari R, Gourinath S. (2014) Crystal Structures and Kinetics of Type III 3-phosphoglycerate dehydrogenase reveal Catalysis by Lysine. FEBS J. doi: 10.1111/febs.13091.

5. Kumar N, Somlata, Mazumder M, Dutta P, Maiti S, and Gourinath S (2014). EhCoactosin stabilizes actin filaments in the protist parasite Entamoeba histolytica. PLoS Pathogens. 10(9):e1004362. 
Recent Peer Reviewed Journals/Books
1. Book Chapter in the book Ameobiasis: SPRINGER Publishers edited by Tomo Nozaki and Alok Bhattacharya. (2015)
Structural Biology of de novo Cysteine Biosynthetic Pathway Enzymes
Isha Raj, Sudhir Kumar, Mohit Mazumder, S. Gourinath

2. Rehman, S. A. A., Verma, A., Mazumder, M., Dhar, S. K., Gourinath, S., (2013) Crystal structure and mode of helicase binding of the C-terminal domain of primase from Helicobacter pylori. J. Bacteriology, 195(12):2826-38.

3. Sudhir Kumar, Isha Raj, Isha Nagpal, N. Subbarao and S. Gourinath (2011). Structural and biochemical studies of Serine Acetyltransferase reveal why the parasite Entamoeba histolytica cannot form Cysteine Synthase complex. J. Biol. Chem. 286 (14), 12533-41. 

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.