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Sneha Sudha Komath

Sneha Sudha Komath

Sneha Sudha Komath
Sneha Sudha Komath
Professor
Centre/School/Special Centre
School of Life Sciences
Room No
406
Off. Phone
011-26704502
Email
sskomath@mail.jnu.ac.in
Personal Webpage
https://jnu.ac.in/Faculty/komath/cv.pdf
Qualifications

Ph.D. University of Hyderabad (Hyderabad), India - 1999
M.Sc. (Chem.) University of Hyderabad (Gold Medalist) - 1991

Areas of Interest/Specialization

Glycobiology/ Biophysical Chemistry 

Experience

2014-present Professor, School of Life Sciences, JNU
2008-2014 Associate Professor, School of Life Sciences, JNU
2003-2008 Assistant Professor, School of Life Sciences, JNU
1999-2002 Lecturer, Department of Chemistry, Panjab University, Chandigarh
2001-2002 Research Associate, University of Wisconsin, Madison, USA (on leave from PU).
1998-1999 Research Associate, Institute of Microbial Technology, Chandigarh.
1993-1998 UGC-JRF/SRF, School of Chemistry, University of Hyderabad.
1991-1993 UGC-JRF, SSCU, Indian Institute of Science, Bangalore. 

Awards & Honours

National Women Bioscientist Award, 2010 

Best Peer Reviewed Publications
  • Komath SS. To each its own: Mechanisms of cross-talk between GPI biosynthesis and cAMP-PKA signaling in Candida albicans versus Saccharomyces cerevisiae. J Biol Chem. 2024 Jul;300(7):107444. doi: 10.1016/j.jbc.2024.107444. Epub 2024 Jun 4. PMID: 38838772; PMCID: PMC11294708.
  • Sethi SC, Bharati M, Kumar Y, Yadav U, Saini H, Alam P, Komath SS*. The ER-Resident Ras Inhibitor 1 (Eri1) of Candida albicans Inhibits Hyphal Morphogenesis via the Ras-Independent cAMP-PKA Pathway. ACS Infect Dis. 2024 Aug 9. doi: 10.1021/acsinfecdis.4c00175. Epub ahead of print. PMID: 39119676.
  • Jain P, Garai P, Sethi SC, Naqvi N, Yadav B, Kumar P, Singh SL, Yadav U, Bhatnagar S, Rahul, Puri N, Muthuswami R*, Komath SS*. Modulation of azole sensitivity and filamentation by GPI15, encoding a subunit of the first GPI biosynthetic enzyme, in Candida albicans. Sci Rep. 2019 Jun 11;9(1):8508. doi: 10.1038/s41598-019-44919-4. PMID: 31186458; PMCID: PMC6559964.
  • Jain P, Sethi SC, Pratyusha VA, Garai P, Naqvi N, Singh S, Pawar K, Puri N, Komath SS*. Ras signaling activates glycosylphosphatidylinositol (GPI) anchor biosynthesis via the GPI-N-acetylglucosaminyltransferase (GPI-GnT) in Candida albicans. J Biol Chem. 2018 Aug 3;293(31):12222-12238. doi: 10.1074/jbc.RA117.001225. Epub 2018 Jun 15. PMID: 29907567; PMCID: PMC6078447.
  • Yadav B, Bhatnagar S, Ahmad MF, Jain P, Pratyusha VA, Kumar P, Komath SS*. First step of glycosylphosphatidylinositol (GPI) biosynthesis cross-talks with ergosterol biosynthesis and Ras signaling in Candida albicans. J Biol Chem. 2014 Feb 7;289(6):3365-82. doi: 10.1074/jbc.M113.528802. Epub 2013 Dec 19. PMID: 24356967; PMCID: PMC3916540.
Recent Peer Reviewed Journals/Books
  • Sethi SC, Bharati M, Kumar Y, Yadav U, Saini H, Alam P, Komath SS*. The ER-Resident Ras Inhibitor 1 (Eri1) of Candida albicans Inhibits Hyphal Morphogenesis via the Ras-Independent cAMP-PKA Pathway. ACS Infect Dis. 2024 Aug 9. doi: 10.1021/acsinfecdis.4c00175. Epub ahead of print. PMID: 39119676.
  • Komath SS*, Fujita M, Hart GW, Ferguson MAJ, Kinoshita T. Glycosylphosphatidylinositol Anchors. In: Varki A, Cummings RD, Esko JD, Stanley P, Hart GW, Aebi M, Mohnen D, Kinoshita T, Packer NH, Prestegard JH, Schnaar RL, Seeberger PH, editors. Essentials of Glycobiology [Internet]. 4th ed. Cold Spring Harbor (NY): Cold Spring Harbor Laboratory Press; 2022. Chapter 12. PMID: 35536964.
  • Sah SK, Shefali S, Yadav A, Som P, Komath SS*. The caspase-like Gpi8 subunit of Candida albicans GPI transamidase is a metal-dependent endopeptidase. Biochem Biophys Res Commun. 2020 Feb 18:S0006-291X(20)30268-0. doi: 10.1016/j.bbrc.2020.02.008. Epub ahead of print. PMID: 32081427.

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.