JNU | RTI | Directory | Contact Us | Emergency Services | List of Holidays
-A A +A

Chinmay K. Mukhopadhyay

Chinmay K. Mukhopadhyay

Chinmay K. Mukhopadhyay
Chinmay K. Mukhopadhyay
Professor
Centre/School/Special Centre
Special Centre for Molecular Medicine
Room No
SCMM
Off. Phone
011-2674-1932, 2673-8738
Email
ckm2300@mail.jnu.ac.in
Personal Webpage
http://www.jnu.ac.in/Faculty/ckm
Qualifications
Ph. D in Biochemistry, 1995
Areas of Interest/Specialization

A. Cross talk between Energy and Iron metabolism.
B. Iron homeostasis in glial cells: implications in Parkinson’s disease.
C. Role of iron in the growth of Leishmania donovani and in interaction with host macrophages 

Experience

1994-1997: Postdoctoral Trainee, Postdoctoral Fellow of the American Heart Association of Northeast Ohio, Department of Cell Biology The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH. USA.
1998-2001: Research Associate, Department of Cell Biology, The Lerner Research Institute, Cleveland Clinic Foundation, Cleveland, OH. USA.
2001-2008: Associate Professor, Special Centre for Molecular Medicine, Jawaharlal Nehru University, India.
2008- till date: Professor, Special Centre for Molecular Medicine, Jawaharlal Nehru University
2005- 2007: Chairperson, Special Centre for Molecular Medicine, Jawaharlal Nehru University 

Awards & Honours

1995: INSA medal for young scientist, Indian National Science Academy
1998: Elsa Albrecht Award, USA
2004: International Senior Research Fellowship, The Wellcome Trust, UK 
2010: Member of Guha Research Conference

International Collaboration/Consultancy

Dr. Paul Fox, Cleveland Clinic Foundation, USA- Posttranscriptional Gene Regulation
Dr. Neena Singh, Case Western Reserve University, USA- Iron in neurodegenerative disorders

Best Peer Reviewed Publications

I. Mukhopadhyay C.K., Mazumder B., Lindley P.F., and Fox P.L. Identification of the prooxidant site of human ceruloplasmin: A model for oxidative damage by copper bound to protein surfaces. Proc. Natl. Acad. Sci. USA, 94:11546-11551, 1997.

II. Mukhopadhyay C.K., Attieh Z.K. and Fox P.L. Role of ceruloplasmin in cellular iron uptake. Science. 279: 714-717, 1998.

III. Mukhopadhyay C.K., Mazumder B., and Fox P.L. Role of Hypoxia Inducible Factor-1 in transcriptional activation of ceruloplasmin by iron deficiency. J. Biol. Chem. 275: 21048-21054, 2000.

IV. Seshadri V., Fox P.L. and Mukhopadhyay C.K. Dual role of insulin in transcriptional regulation of the acute phase reactant ceruloplasmin. J Biol Chem. 277: 27903-27911, 2002

V. Biswas S., Gupta M.K., Chattopadhyay D., and Mukhopadhyay C.K. Insulin induced activation of hypoxia inducible factor-1 requires generation of reactive oxygen species by NADPH oxidase. Am. J. Physiol. Heart and Circulatory Physiology 292(2):H758-66, 2007  

Recent Peer Reviewed Journals/Books
I. Das D, Tapryal N, Goswami SK, Fox PL, and Mukhopadhyay CK. Regulation of Ceruloplasmin in human hepatic cells by redox active copper: Identification of a novel AP-1 site in ceruloplasmin gene. Biochem J. 402(1):135-41, 2007

II. Das NK, Biswas S, Solanki S, Mukhopadhyay CK. Leishmania donovani depletes labile iron pool to exploit iron uptake capacity of macrophage for its intracellular growth. Cellular Microbiology 11:83-94, 2009.

III. Tapryal N, Mukhopadhyay C, Das D, Fox PL, Mukhopadhyay CK. Reactive oxygen species regulate ceruloplasmin by a novel mRNA decay mechanism involving its 3-untranslated region: Implications in neurodegenerative diseases. J Biol Chem. 284:1873-83, 2009
Patents (if any)

None

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.