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Someswar Rao Sagurthi

Someswar Rao Sagurthi

Someswar Rao Sagurthi
Someswar Rao Sagurthi
Associate Professor
Centre/School/Special Centre
Special Centre for Molecular Medicine
Off. Phone
011-26704559
Residence
+ 91 7729822608
Email
drsomeswar@mail.jnu.ac.in, drsomeswar@osmania.ac.in, somu2u@gmail.com
Personal Webpage
https://www.osmania.ac.in/drsomeswarlab
Qualifications

M. Sc -  Biotechnology - JNU New Delhi
PGD: Bioinformatics -  JNU New Delhi
Ph. D: Protein Crystallography - IISc Bangalore
PDF-I : Scripps Research institute, California-USA
PDF-II- Noble Foundation, OK -USA

Areas of Interest/Specialization

Drug Design and Molecular Medicine
Our lab perspective is to emphasize on cellular and molecular phenomena of diseases so as to identify potential drug targets. There are different interactive research tracks, providing for unique interdisciplinary research combined with cutting-edge technologies of the post-genomic era. Because our laboratory has facility for bioinformatics (dry lab) and structural biology (wet lab), we are well equipped to explore and develop novel therapeutic strategies through promising targets.

Experience

I worked as Assistant Professor – Dept of Genetics and Biotech Sept 2013- Aug 2024

Awards & Honours
  • Junior & Senior Research Fellowship (2003- 2008) from Council of Scientific and Industrial Research (CSIR), India.
  • Winner of the best poster presentation competition. International symposium on “Management of Vector- Borne Viruses” International crops research institute for the semi-arid tropics 7-10 February 2006, Hyderabad, India.
  • Third prize for quiz competition in the “National Science Day” 28th February 2002, Jawaharlal Nehru University, New Delhi, India.
  • Got selected for 9thYoung Investigators' Meeting (YIM) March, 2017 in Goa.
  • Got elected as Associate Member of Telangana Academy of Science 2017.
  • Got selected for 10thYoung Investigators' Meeting (YIM) March, 2018 in Tiruvananthapuram.
  • Best researcher Award - International Scientist awards on Engineering, Science and Medicine -2020- VD GOOD TECHNOLOGY
International Collaboration/Consultancy

Metasub - USA

Best Peer Reviewed Publications
  1. Wang X, Pan H, Sagurthi SR, Paris V, Zhuo C, Dixon RA. The protein conformational basis of isoflavone biosynthesis. Communications Biology. 2022 Nov 15;5(1):1249.
  2. Bitla S, Gayatri AA, Puchakayala MR, Bhukya VK, Vannada J, Dhanavath R, Kuthati B, Kothula D, Sagurthi SR*, Atcha KR. Design and synthesis, biological evaluation of bis-(1, 2, 3-and 1, 2, 4)-triazole derivatives as potential antimicrobial and antifungal agents. Bioorganic & Medicinal Chemistry Letters. 2021 Jun 1;41:128004.
  3. Barmukh R, Roorkiwal M, Garg V, Khan AW, German L, Jaganathan D, Chitikineni A, Kholova J, Kudapa H, Sivasakthi K, Samineni, Sagurthi SR Genetic variation in CaTIFY4b contributes to drought adaptation in chickpea. Plant Biotechnology Journal. 2022 Sep;20(9):1701-15.
  4. Mangalarapu M, Vinukonda S, Komaravalli PL, Nagula P, Koduganti RR, Korripally P, Sagurthi SR*. Association of CDKN2BAS gene polymorphism with periodontitis and coronary artery disease from South Indian population. Gene. 2019 Aug 20;710:324-32.
  5. Gudipudi Gopinath, Venu Sankeshi, Shaym perugu, Malini D. Alaparthi, Srinivas Bandaru, Vijay K. Pasala, Prasad Rao Ch, G.L. David Krupadanama, Sagurthi SR*. Design and synthesis of chiral 2H-chromene-N-imidazolo-amino acid conjugates as aldose reductase inhibitors. European Journal of Medicinal Chemistry (2016). 124, 750-762
Recent Peer Reviewed Journals/Books
  1. Gorityala N, Baidya AS, Sagurthi SR*. Genome mining of Mycobacterium tuberculosis: targeting SufD as a novel drug candidate through in silico characterization and inhibitor screening. Frontiers in Microbiology. 2024 Apr 15;15:1369645.
  2. Devi AM, Sankeshi V, Ravali A, Bandaru S, Theendra VK, Sagurthi SR*. Inhibitory effect of Nifedipine on aldose reductase delays cataract progression. Naunyn-Schmiedeberg's Archives of Pharmacology. 2024 Jan;397(1):161-71.
  3. Akkiraju AG, Atcha KR, Sagurthi SR*. Cloning, Purification, and Biophysical Characterization of FemB Protein from Methicillin-Resistant Staphylococcus aureus and Inhibitors Screening. Applied Biochemistry and Biotechnology. 2023 Nov 22:1-9.
Patents (if any)

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A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.