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Syamala Maitreyi Rajala

Syamala Maitreyi Rajala

Syamala Maitreyi Rajala
Syamala Maitreyi Rajala
Assistant Professor
Centre/School/Special Centre
School of Biotechnology
Room No
131
Off. Phone
011- 2673 8752
Email
msrajala@mail.jnu.ac.in, gmaitri@yahoo.com
Personal Webpage
https://jnu.ac.in/Faculty/msrajala
Qualifications

Ph D (Medical Virology) 

Areas of Interest/Specialization

Molecular Virology, Cancer Biology

Experience

2008 to present: Assistant Professor, School of Biotechnology, Jawaharlal Nehru University, New Delhi. 
2006 to 2008: Scientific Officer D, Department of Pathology, Tata Memorial Cancer Hospital, Mumbai. 
2005: Post Doctoral Fellow, Virology Group, International Centre for Genetic Engineering and Biotechnology, New Delhi. 
2001- 2004: Post Doctoral Fellow, Department of Ophthalmology, Dean McGee Eye Institute, Oklahoma University of Health Sciences Centre, Oklahoma City, USA 
2000 to 2001: Research Associate, National Institute of Immunology, New Delhi. 
1995 to 2000:  PhD student, Department of Microbiology, All India Institute of Medical Sciences, New Delhi.  

Awards & Honours

1998: Junior Best Paper Award, XXII National congress of Indian Association of Medical Microbiologists, India 1998
1995 to 1999: Junior Research Fellowship from University Grants Commission, New Delhi 

Best Peer Reviewed Publications
  1. Goyal P, Rajala MS, Reprogramming of glucose metabolism in virus infected cells. Molecular and Cellular Biochemistry (2023) 28;1-10. doi: 10.1007/s11010-023-04669-4
  2. Kumar U, Goyal P, Madni ZK, Kamble K, Gaur V, Rajala MS and Salunke DM. A structure and knowledge-based combinatorial approach to engineering universal scFV antibodies against influenza M2 protein. J of Biomedical Science (2023) 30: 56, doi: 10.1186/s12929-023-00950-2
  3. Vadlamani S, Karmakar R, Kumar A, Rajala MS. Non metabolic role of alpha enolase in virus infections, Molecular Biology Reports (2023) Feb;50(2):1677-1686. doi: 10.1007/s11033-022-08067-9
  4. Verma J, Subbarao N, Rajala MS. Envelope proteins as antiviral drug target. J Drug Target (2020) 28(10):1046-1052. doi: 10.1080/1061186X.2020.1792916
  5. Mittal S, Rajala MS, Heat shock proteins as biomarkers of lung cancer. Cancer Biology and Therapy (2020), doi.org/10.1080/1538-4047.1736482
  6. Mittal S, Kamath A, Joseph AM, Rajala MS. PLCγ1-dependent invasion and migration of cells expressing NSCLC-associated EGFR mutants. Int J Oncology. (2020) 57(4):989-1000. doi: 10.3892/ijo.2020.5112
  7. Mishra S, Goyal P, Kumar D, Chaudhari R, Rajala MS. Experimental validation of influenza A virus Matrix protein (M1) interaction with host cellular alpha enolase and pyruvate kinase. Virology (2020) 549:59-67. doi: 10.1016/j.virol.2020.0
  8. Lal G, Rajala MS (2019). Combination of oncolytic measles virus armed with BNiP3, a pro-apoptotic gene and paclitaxel induces breast cancer cell death. 2019.  Front. Oncol. 8:676, doi: 10.3389/fonc.2018.00676
  9. Lal G, Rajala MS (2018). Recombinant viruses with other anti-cancer therapeutics: a step towards advancement of oncolytic virotherapy. Cancer gene therapy.2018,  DOI:10.1036/s41417-018-0018-1
  10. Kumar D, Tiwari K, Rajala MS. Analysis of A549 cell proteome alterations in response to recombinant Influenza A virus nucleoprotein and its interaction with cellular proteins, a preliminary study. Acta virologica (2017) 61: 56 - 65, doi: 10.4149/av_2017_01_56
  11. Kumar D, Broor S, Rajala MS  (2016). Interaction of Host Nucleolin with Influenza A Virus Nucleoprotein in the Early Phase of Infection Limits the Late Viral Gene Expression. PLoS ONE; 11(10):e0164146. doi:10.1371/journal.pone.0164146
  12. Xiao J, Natarajan K, Rajala MS, Astley RA,  Butler MG, Ramadan R, Chodosh (2005). Vitronectin: A possible determinant of adenovirus type 19 tropism in the human corneal Epithelium. Am. J. Ophthal., 140: 363-369.
  13. Rajala MS,  Rajala RV, Astley RA, Butt L and Chodosh J (2005). Corneal cell survival in Adenovirus type 19 infections requires Phosphoinositide 3-Kinase/Akt activation. J. Virol., 79: 12332-12341.
  14. Rajala MS,  Sullender WM, Prasad AK, Dar L and  Broor S  (2003). Genetic variability among Group A and B Respiratory syncytial virus strain in India. J. Clin.  Microbiol., 41: 2311-2316.
  15. Natarajan K, Rajala MS and  Chodosh  J (2003). Corneal IL-8   expression following adenovirus infection is mediated by c-Src activation in human corneal fibroblasts, J. Immunol., 170: 6234-624.

 

Book Chapter

  1. Karmakar R, Vadlamani S, Verma J, Kumari S, Rajala MS. Molecular pathogenesis of human coronaviruses of 21st century. Coronaviruses’ 2021, Vol 2; 155-190. Edited by Jean-Marc Sabatier, France. Bentham Science Publishers, ISSN (online) 2737-5633, ISBN (online) 978-981-4998-60-4.
Recent Peer Reviewed Journals/Books

 

 

A warm welcome to the modified and updated website of the Centre for East Asian Studies. The East Asian region has been at the forefront of several path-breaking changes since 1970s beginning with the redefining the development architecture with its State-led development model besides emerging as a major region in the global politics and a key hub of the sophisticated technologies. The Centre is one of the thirteen Centres of the School of International Studies, Jawaharlal Nehru University, New Delhi that provides a holistic understanding of the region.

Initially, established as a Centre for Chinese and Japanese Studies, it subsequently grew to include Korean Studies as well. At present there are eight faculty members in the Centre. Several distinguished faculty who have now retired include the late Prof. Gargi Dutt, Prof. P.A.N. Murthy, Prof. G.P. Deshpande, Dr. Nranarayan Das, Prof. R.R. Krishnan and Prof. K.V. Kesavan. Besides, Dr. Madhu Bhalla served at the Centre in Chinese Studies Programme during 1994-2006. In addition, Ms. Kamlesh Jain and Dr. M. M. Kunju served the Centre as the Documentation Officers in Chinese and Japanese Studies respectively.

The academic curriculum covers both modern and contemporary facets of East Asia as each scholar specializes in an area of his/her interest in the region. The integrated course involves two semesters of classes at the M. Phil programme and a dissertation for the M. Phil and a thesis for Ph. D programme respectively. The central objective is to impart an interdisciplinary knowledge and understanding of history, foreign policy, government and politics, society and culture and political economy of the respective areas. Students can explore new and emerging themes such as East Asian regionalism, the evolving East Asian Community, the rise of China, resurgence of Japan and the prospects for reunification of the Korean peninsula. Additionally, the Centre lays great emphasis on the building of language skills. The background of scholars includes mostly from the social science disciplines; History, Political Science, Economics, Sociology, International Relations and language.

Several students of the centre have been recipients of prestigious research fellowships awarded by Japan Foundation, Mombusho (Ministry of Education, Government of Japan), Saburo Okita Memorial Fellowship, Nippon Foundation, Korea Foundation, Nehru Memorial Fellowship, and Fellowship from the Chinese and Taiwanese Governments. Besides, students from Japan receive fellowship from the Indian Council of Cultural Relations.